Mesonephric remnant, hyperplasia or carcinoma in cervix

Mesonephric (Wolffian) duct regresses in females during embryological development; Interestingly, mesonephric remnants in the adnexa are less likely to be GATA3 positive, and more likely to be inhibin positive;

In the first large series of mesonephric lesions reported by Ferry and Scully, the distinction between remnants and hyperplasia was somewhat arbitrary, but all remnants were orderly and well circumscribed, with the largest being 6 mm.

Thus, a size cut-off of 6 mm has since been invoked to aid in distinguishing mesonephric remnants from hyperplasia.

A case of mesonephric adenocarcinoma in cervix from University of Leeds virtual slidebox:

https://www.virtualpathology.leeds.ac.uk/slides/library/view.php?path=%2FResearch_4%2FSlide_Library%2FR_Bishop_Collection%2FCard_index_Set%2FGynae%2F33628.svs