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Case 102

A 63 year old female with some intra-abdominal lesions and here is the cell block of the cytology:


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  1. What's your diagnosis by morphology?

    A: benign endometriosis

    B: carcinoma, favor GI origin

    C: endometrioid carcinoma

    D: High grade serous carcinoma



Answer

The correct answer is B. Specimen contains scattered clusters of atypical glandular cell in a background of necroinflammatory debris, consistent with adenocarcinoma. By imaging: endoscopic finding of a poorly defined 36 mm x 22 mm mass in porta hepatis in gallbladder fossa with several enlarged adjacent lymph nodes is noted. The most likely diagnosis is pancreaticobiliary origin.


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Case credit: UCSD Pathology

Author: Wangpan Jackson Shi, MD

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