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Case 103

A 54-year-old male presented with a left femur lesion.


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One nuclear stain
One nuclear stain

  1. What's a possible morphological impression:

    A: prostate adenocarcinoma

    B: epithelial sarcoma

    C: MPNST

    D: Melanoma

    E: metastatic renal cell carcinoma


Answer

The correct answer is D. The IHC is SOX10. The nested tumor cells with round to spindle shape with nucleoli and clear cytoplasm are seen here.

Case credit: UCSD Pathology

Author: Wangpan Jackson Shi, MD


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