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Case 111

A 67-year-old female with a 4.5 irregular femur lesion and pathologic fracture.


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  1. How do you sign out or further work up for this case?

    A: Benign bone with fibrous tissue and granulation tissue

    B: Spindle cell lesion, rule out sarcoma

    C: Fibrous dysplasia, rule out osteosarcoma

    D: Rule out metastatic carcinoma



Answer

This is a challenging case without history, the patient has a history of metastatic breast carcinoma with lobular features and the tumor in the femur is positive for Pan-CK, weak staining for GATA3.

Case credit: UCSD Pathology

Author: Wangpan Jackson Shi, MD

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