Case 121
- Wangpan Shi
- May 26
- 1 min read
A 77-year-old female with a colon mass and she was found to have an ovarian mass as well:




What is your diagnosis by morphology?
A: Colon adenocarcinoma
B: High grade serous carcinoma
C: Sertoli-Leydig tumor
D: IMT
Answer
The correct answer is B. This is a case of high grade serous carcinoma. The low power architecture favors a tumor invades from outside of the colonic tract and the slit like pattern with round oval cells are not commonly seen in colon adenocarcinoma.
Case credit: UCSD Pathology
Author: Wangpan Jackson Shi, MD

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