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Case 19

Updated: Jan 23

A 70-year-old male was found to have a T3 lytic lesion.


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  1. What is a panel of stain you will order for further work-up?


IHC

  • Pan-keratin

  • CD45/LCA

  • CK7, CK20

  • Myogenin

You can vote for more than one answer.


One particular stain that helps
One particular stain that helps

Answer

This case is a metastatic prostatic adenocarcinoma. By morphology, the monotonous, prominent nucleoli, and focal acinar/gland/rosette formation may tip you off. The stain is NKX 3.1; NKX 2.2 is a stain helpful for Ewing sarcoma.

Case credit: UCSD Pathology

Author: Wangpan Jackson Shi, MD


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