Case 21

A painless 3 cm mandibular mass was found in a 30-year-old male.

1. What is the diagnosis?

   A: Fibrous dysplasia

   B: Osteoblastoma

   C: Osteoid osteoma

   D: Cemento-ossifying fibroma

   
   

Answer

The correct answer is cemento-ossifying fibroma. The clue here is cement-like ossicles embedded in fibrous stroma.

cement-like ossicles, not the typical woven bone

2. Which of the following conditions is typically associated with hyperparathyroidism jaw tumor syndrome?

A: Fibrous dysplasia

B: Osteoblastoma

C: Osteoid osteoma

D: Cemento-ossifying fibroma

Answer

The correct answer is D. It is associated with a triad of tumors: multiple cement-ossifying fibromas in the maxilla and mandible, parathyroid adenomas or carcinomas, renal and uterine tumors.

References:

1.Aburas S, Bandura P, Al-Ibraheem A, Berger S, Meier M, Turhani D. A large maxillary cemento-ossifying fibroma superimposed with solitary bone cyst documented over 18 years: A case report. Int J Surg Case Rep. 2020;68:257-262. doi: 10.1016/j.ijscr.2020.03.011. Epub 2020 Mar 7. PMID: 32199251; PMCID: PMC7082601.

2.https://www.pathologyoutlines.com/topic/mandiblemaxillaossifyingfibroma.html

Case credit: UCSD Pathology

Author: Wangpan Jackson Shi, MD