top of page

UCSD Surgical Pathology Unknowns
Search
All Posts
A case of HGPIN with foci suspicious for cancer
lesson: sneaky glands with prominent nucleoli with adjacent big glands show similar cytomorphology; you might want to consider everything...
A case of challenging prostate adenocarcinoma
No nucleoli but relative rigid lumen with some dirty secretion Case credit: Dong Ren, MD UC Irvine
Molecular testings of endometrial cancer: talk from Dr. Anca Oniscu from BAGP teaching session
Only POLE shows clearly favorable survival compared to copy-number high (TP53) group FIGO 2023 for endometrial cancer Aggressive...
A case of NTRK-rearranged neoplasm
Coexpression of S100 and CD34 by immunohistochemistry is the key. These tumors exhibit a broad range of morphologies and histological...
Frozen section in ovary tumor
If diagnosis of malignancy or ‘ at least borderline ’ is made at FS, surgical staging can be performed immediately, averting a second...
Case 24
A 40-year-old women with a 4.5 cm ovary mass. Here is the frozen: How you would call the frozen? Which big category? Answer The correct...
When to think about myoepithelioma?
A list of the top ddx:
Case 23
A 63-year-old female with a 3.2 cm mass at left breast. What's the diagnosis? A: Invasive ductal carcinoma B: Invasive lobular carcinoma...
Case 22
A 60-year-old man with obstructive jaundice. A Bile duct biopsy was performed: What's your diagnosis? A: Stent effect and reactive atypia...
New entity: Myoepithelioma-like Tumors of the Vulvar Region
ER EMA+; INI1 loss
Clear cell RCC morphology but you see smooth muscle stroma?
Credit: Dr. Ren Dong from UC Irvine RCCFMS is short for renal cell carcinoma with fibromyomatous stroma. The top ddx are clear cell RCC...
Flat lesion in urothelium, hyperplasia or dysplasia?
For flat lesion, dysplasia is not well-recognised now; either normal/hyperplasia versus CIS. A diagnosis of dysplasia needs comment: An...
Case 21
A painless 3 cm mandibular mass was found in a 30-year-old male. What is the diagnosis? A: Fibrous dysplasia B: Osteoblastoma C: Osteoid...
Case 20
A 25-year-old female presented with oral progestin use and found to have a large cervical polyp. What is the diagnosis? A: endometrioid...
What does atypical mucinous glandular proliferation mean in a endometrial biopsy?
The diagnostic line example is: -Atypical mucinous glandular proliferation (see comment). COMMENT : Sections show crowded glands and...
Tumor metastatic to bone
A list of sarcoma that can met to lymph node is below: clear cell sarcoma, angiosarcoma, epithelioid sarcoma, rhabdomyosarcoma, and...
Does micropapillae equal to serous?
A helpful clue for serous morphology is the irregular luminal border (micropapillae or tuftings of cells). In this example, the...
Case 19
A 70-year-old male was found to have a T3 lytic lesion. What is a panel of stain you will order for further work-up? One particular stain...
bottom of page